Family · sexual
Leuprolide
Leuprorelin, Lupron, Eligard, Prostap
A synthetic nonapeptide GnRH (gonadotropin-releasing hormone) agonist. Continuous exposure first stimulates the pituitary (an initial 'flare' of LH/FSH and a testosterone/estrogen surge over ~5-12 days), then down-regulates GnRH receptors, producing sustained suppression of sex hormones (reversible medical castration).
Well-established prescription drug with decades of clinical data. Approved by the FDA in 1989; a first-line hormonal therapy in several conditions.
- Advanced prostate cancer (androgen deprivation)
- Endometriosis and uterine fibroids
- Central precocious puberty
- Adjunct in assisted-reproduction protocols
Educational overview only — no dosing instructions in the public hub. Prescription drug administered under specialist supervision.
Initial tumour 'flare' can transiently worsen symptoms (bone pain, urinary obstruction); hypogonadism effects — hot flushes, reduced bone density, sexual dysfunction, mood changes, metabolic and cardiovascular considerations. Prescription-only; use requires medical oversight.
A regulated pharmaceutical product should be obtained only through licensed pharmacies with a valid prescription; batch/label integrity and cold-chain matter.
Approved prescription medicine (Rx) in the US, EU and most jurisdictions; not a research-use-only compound and not available over the counter.
Frequently asked questions
- What is Leuprolide used for?
- Advanced prostate cancer (androgen deprivation). Endometriosis and uterine fibroids. Central precocious puberty. Adjunct in assisted-reproduction protocols. Well-established prescription drug with decades of clinical data. Approved by the FDA in 1989; a first-line hormonal therapy in several conditions.
- Is Leuprolide legal in Europe?
- Approved prescription medicine (Rx) in the US, EU and most jurisdictions; not a research-use-only compound and not available over the counter.
- What are the risks and side effects of Leuprolide?
- Initial tumour 'flare' can transiently worsen symptoms (bone pain, urinary obstruction); hypogonadism effects — hot flushes, reduced bone density, sexual dysfunction, mood changes, metabolic and cardiovascular considerations. Prescription-only; use requires medical oversight.
- How is the quality of Leuprolide assessed?
- A regulated pharmaceutical product should be obtained only through licensed pharmacies with a valid prescription; batch/label integrity and cold-chain matter.